GenomeScope 2.0

Estimate genome heterozygosity, repeat content, and size from sequencing reads using a kmer-based statistical approach.

Information

The code is open source on Github: github.com/tbenavi1/genomescope2.0

Statistical work by Gregory Vurture and Fritz Sedlazeck

Polyploid 2.0 model by T. Rhyker Ranallo-Benavidez

Web application by Maria Nattestad

Principal investigator: Mike Schatz

For questions about the science, email: Mike Schatz at mschatz@cs.jhu.edu

Please cite: T. Rhyker Ranallo-Benavidez et al. (2020) GenomeScope 2.0 and Smudgeplot for reference-free profiling of polyploid genomes. Nature Communications. https://doi.org/10.1038/s41467-020-14998-3