Estimate genome heterozygosity, repeat content, and size from sequencing reads using a kmer-based statistical approach.


The code is open source on Github:

Statistical work by Gregory Vurture and Fritz Sedlazeck

Web application by Maria Nattestad

Principal investigator: Mike Schatz

For questions about the science, email: Mike Schatz at

Please cite: Vurture et al. (2017) GenomeScope: Fast reference-free profiling from short reads. Bioinformatics. doi:

Also try out GenomeScope 2.0